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Target
L-selectin
Ligand
BDBM50450369
Substrate
n/a
Meas. Tech.
ChEMBL_199996 (CHEMBL810880)
IC50
>1000000±n/a nM
Citation
 Tsukida, T; Hiramatsu, Y; Tsujishita, H; Kiyoi, T; Yoshida, M; Kurokawa, K; Moriyama, H; Ohmoto, H; Wada, Y; Saito, T; Kondo, H Studies on selection blockers. 5. Design, synthesis, and biological profile of sialyl Lewis x mimetics based on modified serine-glutamic acid dipeptides. J Med Chem 40:3534-41 (1997) [PubMed]  Article 
Target
Name:
L-selectin
Synonyms:
LYAM1_MOUSE | Leukocyte adhesion molecule-1 | Lnhr | Ly-22 | Ly22 | Sell
Type:
PROTEIN
Mol. Mass.:
42288.63
Organism:
Mus musculus
Description:
ChEMBL_199996
Residue:
372
Sequence:
MVFPWRCEGTYWGSRNILKLWVWTLLCCDFLIHHGTHCWTYHYSEKPMNWENARKFCKQNYTDLVAIQNKREIEYLENTLPKSPYYYWIGIRKIGKMWTWVGTNKTLTKEAENWGAGEPNNKKSKEDCVEIYIKRERDSGKWNDDACHKRKAALCYTASCQPGSCNGRGECVETINNHTCICDAGYYGPQCQYVVQCEPLEAPELGTMDCIHPLGNFSFQSKCAFNCSEGRELLGTAETQCGASGNWSSPEPICQVVQCEPLEAPELGTMDCIHPLGNFSFQSKCAFNCSEGRELLGTAETQCGASGNWSSPEPICQETNRSFSKIKEGDYNPLFIPVAVMVTAFSGLAFLIWLARRLKKGKKSQERMDDPY
  
Inhibitor
Name:
BDBM50450369
Synonyms:
SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLex | sialyl LewisX
Type:
Small organic molecule
Emp. Form.:
C31H52N2O23
Mol. Mass.:
820.7442
SMILES:
[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]([C@H](O)CO)[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](NC(C)=O)C=O)[C@@H]1O)C(O)=O)[C@H](O)[C@H](O)CO
Structure:
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