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Target
L-selectin
Ligand
BDBM50060514
Substrate
n/a
Meas. Tech.
ChEMBL_199996 (CHEMBL810880)
IC50
6000±n/a nM
Citation
 Tsukida, T; Hiramatsu, Y; Tsujishita, H; Kiyoi, T; Yoshida, M; Kurokawa, K; Moriyama, H; Ohmoto, H; Wada, Y; Saito, T; Kondo, H Studies on selection blockers. 5. Design, synthesis, and biological profile of sialyl Lewis x mimetics based on modified serine-glutamic acid dipeptides. J Med Chem 40:3534-41 (1997) [PubMed]  Article 
Target
Name:
L-selectin
Synonyms:
LYAM1_MOUSE | Leukocyte adhesion molecule-1 | Lnhr | Ly-22 | Ly22 | Sell
Type:
PROTEIN
Mol. Mass.:
42288.63
Organism:
Mus musculus
Description:
ChEMBL_199996
Residue:
372
Sequence:
MVFPWRCEGTYWGSRNILKLWVWTLLCCDFLIHHGTHCWTYHYSEKPMNWENARKFCKQNYTDLVAIQNKREIEYLENTLPKSPYYYWIGIRKIGKMWTWVGTNKTLTKEAENWGAGEPNNKKSKEDCVEIYIKRERDSGKWNDDACHKRKAALCYTASCQPGSCNGRGECVETINNHTCICDAGYYGPQCQYVVQCEPLEAPELGTMDCIHPLGNFSFQSKCAFNCSEGRELLGTAETQCGASGNWSSPEPICQVVQCEPLEAPELGTMDCIHPLGNFSFQSKCAFNCSEGRELLGTAETQCGASGNWSSPEPICQETNRSFSKIKEGDYNPLFIPVAVMVTAFSGLAFLIWLARRLKKGKKSQERMDDPY
  
Inhibitor
Name:
BDBM50060514
Synonyms:
(S)-4-Methylcarbamoyl-4-[(R)-2-(2-tetradecyl-hexadecanoylamino)-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-propionylamino]-butyric acid | CHEMBL119836
Type:
Small organic molecule
Emp. Form.:
C45H85N3O10
Mol. Mass.:
828.1705
SMILES:
CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC)C(=O)N[C@H](COC1OC(C)C(O)C(O)C1O)C(=O)N[C@@H](CCC(O)=O)C(=O)NC
Structure:
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