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Target
Glutamate receptor 4
Ligand
BDBM50060631
Substrate
n/a
Meas. Tech.
ChEMBL_90301 (CHEMBL878454)
Ki
207±n/a nM
Citation
 Jane, DE; Hoo, K; Kamboj, R; Deverill, M; Bleakman, D; Mandelzys, A Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes. J Med Chem 40:3645-50 (1997) [PubMed]  Article 
Target
Name:
Glutamate receptor 4
Synonyms:
GLUR4 | GRIA4 | GRIA4_HUMAN | Glutamate receptor AMPA 3/4 | Glutamate receptor ionotropic AMPA | Glutamate receptor ionotropic, AMPA 4
Type:
PROTEIN
Mol. Mass.:
100881.87
Organism:
Homo sapiens (Human)
Description:
ChEMBL_468628
Residue:
902
Sequence:
MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKLTFSEAIRNKARLSITGSVGENGRVLTPDCPKAVHTGTAIRQSSGLAVIASDLP
  
Inhibitor
Name:
BDBM50060631
Synonyms:
(S)-2-Amino-3-(5-nitro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-propionic acid | CHEMBL121191
Type:
Small organic molecule
Emp. Form.:
C7H8N4O6
Mol. Mass.:
244.1616
SMILES:
N[C@@H](Cn1cc([N+]([O-])=O)c(=O)[nH]c1=O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: