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Target
Cannabinoid receptor 1
Ligand
BDBM50056457
Substrate
n/a
Meas. Tech.
ChEMBL_46295 (CHEMBL661064)
Ki
598±n/a nM
Citation
 Sheskin, T; Hanus, L; Slager, J; Vogel, Z; Mechoulam, R Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. J Med Chem 40:659-67 (1997) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50056457
Synonyms:
(8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-8,11,14-trienamide | (Z,Z,Z)-icosa-8,11,14-trienoylethanolamide | 8,11,14-Eicosatrienoylethanolamide | Anandamide (20.3,n-6) | CHEMBL121229 | HGLEA | Homo-gamma-linolenylethanolamide | N-(8Z,11Z,14Z-icosatrienoyl)-ethanolamide
Type:
Small organic molecule
Emp. Form.:
C22H39NO2
Mol. Mass.:
349.5506
SMILES:
CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(=O)NCCO
Structure:
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