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Target
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Ligand
BDBM50368782
Substrate
n/a
Meas. Tech.
ChEMBL_202902 (CHEMBL807654)
Ki
10000±n/a nM
Citation
 Kenny, B; Ballard, S; Blagg, J; Fox, D Pharmacological options in the treatment of benign prostatic hyperplasia. J Med Chem 40:1293-315 (1997) [PubMed]  Article 
Target
Name:
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Synonyms:
S5A2_RAT | Srd5a2 | Steroid 5-alpha-reductase | Steroid 5-alpha-reductase 2
Type:
PROTEIN
Mol. Mass.:
28784.15
Organism:
Rattus norvegicus
Description:
ChEMBL_205054
Residue:
254
Sequence:
MQIVCHQVPVLAGSATLATMGTLILCLGKPASYGKHTESVSSGVPFLPARIAWFLQELPSFVVSVGMLAWQPRSLFGPPGNVLLALFSAHYFHRTFIYSLLTRGRPFPAVLFLRATAFCIGNGLLQAYYLVYCAEYPEEWYTDVRFSFGVFLFILGMGINIHSDYTLRQLRKPGEVIYRIPRGGLFTYVSGANFLGEIIEWIGYALATWSVPAFAFAFFTLCFLGMQAFYHHRFYLKMFKDYPKSRKALIPFIF
  
Inhibitor
Name:
BDBM50368782
Synonyms:
Bexlosteride | CHEMBL24955 | LY-191704
Type:
Small organic molecule
Emp. Form.:
C14H16ClNO
Mol. Mass.:
249.736
SMILES:
CN1[C@@H]2CCc3cc(Cl)ccc3[C@H]2CCC1=O
Structure:
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