Reaction Details Report a problem with these data
Target
Phosphoglycerate kinase
Ligand
BDBM50067780
Substrate
n/a
Meas. Tech.
ChEMBL_155739 (CHEMBL759844)
Kd
2130000±n/a nM
Citation
 Jakeman, DL; Ivory, AJ; Williamson, MP; Blackburn, GM Highly potent bisphosphonate ligands for phosphoglycerate kinase. J Med Chem 41:4439-52 (1998) [PubMed]  Article 
Target
Name:
Phosphoglycerate kinase
Synonyms:
PGK1 | PGK_YEAST | Phosphoglycerate kinase 1
Type:
PROTEIN
Mol. Mass.:
44741.88
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_155739
Residue:
416
Sequence:
MSLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK
  
Inhibitor
Name:
BDBM50067780
Synonyms:
Hexane-1,6-bisphosphonic Acid
Type:
Small organic molecule
Emp. Form.:
C6H12O6P2
Mol. Mass.:
242.1056
SMILES:
[O-]P([O-])(=O)CCCCCCP([O-])([O-])=O
Structure:
Search PDB for entries with ligand similarity: