Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50010617
Substrate
n/a
Meas. Tech.
ChEMBL_61320 (CHEMBL670095)
Ki
12000±n/a nM
Citation
 Cervetto, L; Demontis, GC; Giannaccini, G; Longoni, B; Macchia, B; Macchia, M; Martinelli, A; Orlandini, E N-n-Propyl-substituted 3-(dimethylphenyl)piperidines display novel discriminative properties between dopamine receptor subtypes: synthesis and receptor binding studies. J Med Chem 41:4933-8 (1999) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50010617
Synonyms:
(-)-3-(1-Propyl-piperidin-3-yl)-phenol | (S)-3-(1-propylpiperidin-3-yl)phenol | 3-((S)-1-Propyl-piperidin-3-yl)-phenol | 3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP,(+) | CHEMBL7549 | Preclamol
Type:
Small organic molecule
Emp. Form.:
C14H21NO
Mol. Mass.:
219.3226
SMILES:
CCCN1CCC[C@H](C1)c1cccc(O)c1
Structure:
Search PDB for entries with ligand similarity: