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Target
Peptidyl-prolyl cis-trans isomerase FKBP1A
Ligand
BDBM50068569
Substrate
n/a
Meas. Tech.
ChEMBL_66273 (CHEMBL678143)
Ki
50±n/a nM
Citation
 Hamilton, GS; Steiner, JP Immunophilins: beyond immunosuppression. J Med Chem 41:5119-43 (1999) [PubMed]  Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase FKBP1A
Synonyms:
12 kDa FK506-binding protein | 12 kDa FKBP | FK506-binding protein 1A | FK506-binding protein 1A (FKBP12) | FKB1A_HUMAN | FKBP-12 | FKBP-1A | FKBP1 | FKBP12 | FKBP1A | Immunophilin FKBP12 | PPIase | PPIase FKBP1A | Peptidyl-prolyl cis-trans isomerase (FKBP) | Rotamase | RyR1/FKBP12 | mTOR/FKBP12A/FKBP12B
Type:
Isomerase
Mol. Mass.:
11953.09
Organism:
Homo sapiens (Human)
Description:
P62942
Residue:
108
Sequence:
MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
  
Inhibitor
Name:
BDBM50068569
Synonyms:
27-Ethyl-30-(1-hydroxy-2-methyl-hex-4-enyl)-3,6-diisobutyl-18,33-diisopropyl-4,7,9,12,15,16,21,25,31-nonamethyl-1,4,7,10,13,16,19,22,25,28decaaza-cyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone | CHEMBL2371001
Type:
Small organic molecule
Emp. Form.:
C54H95N11O12
Mol. Mass.:
1090.3986
SMILES:
[H][C@@]1([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)N(C)C(=O)[C@@H](NC(=O)[C@@H](C)NC(=O)CN(C)C(=O)[C@H](CC)NC1=O)C(C)C)C(C)C
Structure:
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