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Target
B2 bradykinin receptor
Ligand
BDBM50062862
Substrate
n/a
Meas. Tech.
ChEMBL_40262 (CHEMBL653278)
IC50
1700±n/a nM
Citation
 Abe, Y; Kayakiri, H; Satoh, S; Inoue, T; Sawada, Y; Imai, K; Inamura, N; Asano, M; Hatori, C; Katayama, A; Oku, T; Tanaka, H A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 1. Construction of the basic framework. J Med Chem 41:564-78 (1998) [PubMed]  Article 
Target
Name:
B2 bradykinin receptor
Synonyms:
B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKRB2_CAVPO | Bradykinin B2 receptor
Type:
n/a
Mol. Mass.:
42217.03
Organism:
Cavia porcellus
Description:
n/a
Residue:
372
Sequence:
MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHKSSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGHNVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTERRATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCLNPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWARSSSEGTPPGLL
  
Inhibitor
Name:
BDBM50062862
Synonyms:
3-Chloro-8-(2,6-dibromo-benzyloxy)-2-methyl-imidazo[1,2-a]pyridine | CHEMBL346458
Type:
Small organic molecule
Emp. Form.:
C15H11Br2ClN2O
Mol. Mass.:
430.522
SMILES:
Cc1nc2c(OCc3c(Br)cccc3Br)cccn2c1Cl
Structure:
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