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Target
P2Y purinoceptor 1
Ligand
BDBM50076461
Substrate
n/a
Meas. Tech.
ChEMBL_147722 (CHEMBL759192)
IC50
475±n/a nM
Citation
 Nandanan, E; Camaioni, E; Jang, SY; Kim, YC; Cristalli, G; Herdewijn, P; Secrist, JA; Tiwari, KN; Mohanram, A; Harden, TK; Boyer, JL; Jacobson, KA Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists. J Med Chem 42:1625-38 (1999) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
P2RY1 | P2RY1_MELGA
Type:
n/a
Mol. Mass.:
41199.64
Organism:
Meleagris gallopavo
Description:
n/a
Residue:
362
Sequence:
MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
  
Inhibitor
Name:
BDBM50076461
Synonyms:
CHEMBL42879 | Phosphoric acid mono-[5-(2-allylsulfanyl-6-methylamino-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl] ester
Type:
Small organic molecule
Emp. Form.:
C14H21N5O9P2S
Mol. Mass.:
497.357
SMILES:
CNc1nc(SCC=C)nc2n(cnc12)C1CC(OP(O)(O)=O)C(COP(O)(O)=O)O1
Structure:
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