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Target
Adenosine transporter 1
Ligand
BDBM50105133
Substrate
n/a
Meas. Tech.
ChEMBL_149711 (CHEMBL755808)
Ki
4600±n/a nM
Citation
 Klenke, B; Stewart, M; Barrett, MP; Brun, R; Gilbert, IH Synthesis and biological evaluation of s-triazine substituted polyamines as potential new anti-trypanosomal drugs. J Med Chem 44:3440-52 (2001) [PubMed]  Article 
Target
Name:
Adenosine transporter 1
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
51044.02
Organism:
Trypanosoma brucei
Description:
ChEMBL_31141
Residue:
463
Sequence:
MLGFDSANEFIVYVTFLFFGMSVVVVTNSIFSMPFFFIEYYKYAQGKPDAKPEDPKFWKHMFTYYSIAAFLVELVLASLMLTPIGRRISVTVRLGVGLVIPIVLVFSVMMVTIVTTTETGAKVTIMLIAIANGVAMTLCDAGNAALIAPFPTKFYSSVVWGIAVCGVVTSFFSIVIKASMGGGYHNMLIQSRIYFGLVMFMQVISCALLVLLRKNPYAQKYAAEFRYAARKGIDDKGADGDEGNGAAKGPADQDDDPHGGDDTDKGNVMTATVDPDTMKDMDQVENITTSQQMLMARVWNVFWRVWPMLFACFMVFFTTFLVYPAVYFAIKADTGDGWYLTIAAALFNLGDFLSRLCLQFKALHVSPRWVLIGTFARMLLIIPLVLCVRSIITGPWLPYILVHAWGFTYGYYGGISQIYAPRTGSLTTAGERSLAANWTIISLLGGIFVGAMFALAVNEGLPK
  
Inhibitor
Name:
BDBM50105133
Synonyms:
CHEMBL541581 | N1,N9-Di(3-(((4-amino-6-(dimethylamino-1,3,5-triazin-2-yl)methyl)amino)propyl)-1,12dodecanediamine Heptachloride
Type:
Small organic molecule
Emp. Form.:
C42H78N24
Mol. Mass.:
919.2295
SMILES:
CN(C)c1nc(N)nc(CN(CCCNCCCCCCCCCCCCNCCCN(Cc2nc(N)nc(n2)N(C)C)Cc2nc(N)nc(n2)N(C)C)Cc2nc(N)nc(n2)N(C)C)n1
Structure:
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