Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50096003
Substrate
n/a
Meas. Tech.
ChEMBL_103899 (CHEMBL711481)
Ki
470±n/a nM
Citation
Orita, M; Yamamoto, S; Katayama, N; Aoki, M; Takayama, K; Yamagiwa, Y; Seki, N; Suzuki, H; Kurihara, H; Sakashita, H; Takeuchi, M; Fujita, S; Yamada, T; Tanaka, A Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography. J Med Chem 44:540-7 (2001) [PubMed] Article
More Info.:
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA