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Target
Alpha-1D adrenergic receptor
Ligand
BDBM50098355
Substrate
n/a
Meas. Tech.
ChEMBL_33678 (CHEMBL646819)
Ki
0.780±n/a nM
Citation
 Boyd, RE; Press, JB; Rasmussen, CR; Raffa, RB; Codd, EE; Connelly, CD; Li, QS; Martinez, RP; Lewis, MA; Almond, HR; Reitz, AB Alpha(2) adrenoceptor agonists as potential analgesic agents. 3. Imidazolylmethylthiophenes. J Med Chem 44:863-72 (2001) [PubMed]  Article 
Target
Name:
Alpha-1D adrenergic receptor
Synonyms:
ADA1D_HUMAN | ADRA1A | ADRA1D | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1D-adrenoceptor | Alpha 1D-adrenoreceptor | Alpha adrenergic receptor (1a and 1d) | Alpha-1D adrenoceptor | Alpha-adrenergic receptor 1a | adrenergic Alpha1D
Type:
Enzyme Catalytic Domain
Mol. Mass.:
60485.82
Organism:
Homo sapiens (Human)
Description:
adrenergic Alpha1D ADRA1D HUMAN::P25100
Residue:
572
Sequence:
MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEMQAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVEAVSLGVPHEVAEGATCQAYELADYSNLRETDI
  
Inhibitor
Name:
BDBM50098355
Synonyms:
4-[1-(3-Methyl-thiophen-2-yl)-ethyl]-1H-imidazole | 4-[1-(3-Methyl-thiophen-2-yl)-ethyl]-1H-imidazole; hydrochloride | CHEMBL1237160 | CHEMBL170960
Type:
Small organic molecule
Emp. Form.:
C10H12N2S
Mol. Mass.:
192.281
SMILES:
CC(c1cnc[nH]1)c1sccc1C
Structure:
Search PDB for entries with ligand similarity: