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Target
Ricin
Ligand
BDBM50108004
Substrate
n/a
Meas. Tech.
ChEMBL_63579 (CHEMBL677513)
IC50
600000±n/a nM
Citation
 Miller, DJ; Ravikumar, K; Shen, H; Suh, JK; Kerwin, SM; Robertus, JD Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition. J Med Chem 45:90-8 (2001) [PubMed]  Article 
Target
Name:
Ricin
Synonyms:
RICI_RICCO
Type:
PROTEIN
Mol. Mass.:
64090.82
Organism:
Ricinus communis
Description:
ChEMBL_1286970
Residue:
576
Sequence:
MKPGGNTIVIWMYAVATWLCFGSTSGWSFTLEDNNIFPKQYPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAITHLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYSTGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALMVYRCAPPPSSQFSLLIRPVVPNFNADVCMDPEPIVRIVGRNGLCVDVRDGRFHNGNAIQLWPCKSNTDANQLWTLKRDNTIRSNGKCLTTYGYSPGVYVMIYDCNTAATDATRWQIWDNGTIINPRSSLVLAATSGNSGTTLTVQTNIYAVSQGWLPTNNTQPFVTTIVGLYGLCLQANSGQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVKILSCGPASSGQRWMFKNDGTILNLYSGLVLDVRASDPSLKQIILYPLHGDPNQIWLPLF
  
Inhibitor
Name:
BDBM50108004
Synonyms:
4-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)-ethyl]-benzoic acid | CHEMBL367184
Type:
Small organic molecule
Emp. Form.:
C15H14N4O3
Mol. Mass.:
298.2967
SMILES:
Nc1nc2[nH]c(CCc3ccc(cc3)C(O)=O)cc2c(=O)[nH]1
Structure:
Search PDB for entries with ligand similarity: