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Target
Melanocortin receptor 5
Ligand
BDBM50115360
Substrate
n/a
Meas. Tech.
ChEMBL_104264 (CHEMBL711701)
EC50
263±n/a nM
Citation
 Holder, JR; Bauzo, RM; Xiang, Z; Haskell-Luevano, C Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors: part 2 modifications at the Phe position. J Med Chem 45:3073-81 (2002) [PubMed]  Article 
Target
Name:
Melanocortin receptor 5
Synonyms:
MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R)
Type:
Enzyme
Mol. Mass.:
36966.58
Organism:
Mus musculus (Mouse)
Description:
P41149
Residue:
325
Sequence:
MNSSSTLTVLNLTLNASEDGILGSNVKNKSLACEEMGIAVEVFLTLGLVSLLENILVIGAIVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDSMICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIYYESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRTSMKGAITLTMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQEMRRTFKEIVCCHGFRRPCRLLGGY
  
Inhibitor
Name:
BDBM50115360
Synonyms:
2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid {1-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butyl}-amide | CHEMBL102688
Type:
Small organic molecule
Emp. Form.:
C36H45N11O5
Mol. Mass.:
711.8132
SMILES:
CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)NC1(CCc2ccccc2C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Structure:
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