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TargetAdenosine A2b receptor
LigandBDBM50116458
Substrate/Competitorn/a
Meas. Tech.ChEMBL_4798
Ki 7000±n/a nM
Citation Müller, CEThorand, MQurishi, RDiekmann, MJacobson, KAPadgett, WLDaly, JW Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. J Med Chem45:3440-50 (2002) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine A2b receptor
Name:Adenosine A2b receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:36130.09
Organism:Mus musculus
Description:ChEMBL_11831
Residue:332
Sequence:
MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFA
IPFAITISLGFCTDFHGCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGT
RARGIIAVLWVLAFGIGLTPFLGWNSKDSATSNCTELGDGIANKSCCPVTCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFMVACKQLQRMELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYS
FHKIISRYVLCQAETKGGSGQAGAQSTLSLGL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50116458
NameBDBM50116458
Synonyms:1-Methyl-2-phenyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one | CHEMBL117962
TypeSmall organic molecule
Emp. Form.C14H13N5O
Mol. Mass.267.2859
SMILESCn1c(nc2NC(=O)N3CCN=C3c12)-c1ccccc1 |c:11|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a