Reaction Details Report a problem with these data
Target
P2Y purinoceptor 4
Ligand
BDBM50366480
Substrate
n/a
Meas. Tech.
ChEMBL_147880 (CHEMBL757042)
EC50
1800±n/a nM
Citation
 Jacobson, KA; Jarvis, MF; Williams, M Purine and pyrimidine (P2) receptors as drug targets. J Med Chem 45:4057-93 (2002) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 4
Synonyms:
P2RY4_RAT | P2Y purinoceptor 4 | P2ry4 | P2y4 | Pyrimidinergic receptor P2Y4
Type:
PROTEIN
Mol. Mass.:
40908.48
Organism:
Rattus norvegicus
Description:
ChEMBL_147880
Residue:
361
Sequence:
MTSAESLLFTSLGPSPSSGDGDCRFNEEFKFILLPMSYAVVFVLGLALNAPTLWLFLFRLRPWDATATYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGLCKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRAIRWGRPRFASLLCLGVWLVVAGCLVPNLFFVTTNANGTTILCHDTTLPEEFDHYVYFSSAVMVLLFGLPFLITLVCYGLMARRLYRPLPGAGQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYQARLLQADCHVLNIVNVVYKVTRPLASANSCLDPVLYLFTGDKYRNQLQQLCRGSKPKPRTAASSLALVTLHEESISRWADTHQDSTFSAYEGDRL
  
Inhibitor
Name:
BDBM50366480
Synonyms:
ADENOSINE TRIPHOSPHATE | ATP
Type:
Small organic molecule
Emp. Form.:
C10H16N5O13P3
Mol. Mass.:
507.181
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: