Reaction Details
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Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Ligand
BDBM50110692
Substrate
n/a
Meas. Tech.
ChEMBL_197997 (CHEMBL798975)
IC50
2960±n/a nM
Citation
McCluskey, A; Sim, AT; Sakoff, JA Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies. J Med Chem 45:1151-75 (2002) [PubMed] Article More Info.:
Target
Name:
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Synonyms:
PP1G_HUMAN | PPP1CC | Serine/threonine protein phosphatase PP1-gamma catalytic subunit
Type:
PROTEIN
Mol. Mass.:
36983.39
Organism:
Homo sapiens (Human)
Description:
ChEMBL_473188
Residue:
323
Sequence:
MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPVTPPRGMITKQAKK
Inhibitor
Name:
BDBM50110692
Synonyms:
7-Oxa-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid monoethyl ester | CHEMBL16701
Type:
Small organic molecule
Emp. Form.:
C10H14O5
Mol. Mass.:
214.2152
SMILES:
CCOC(=O)C1[C@H]2CCC(O2)C1C(O)=O
Structure:
