Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50128095
Substrate
n/a
Meas. Tech.
ChEMBL_46981 (CHEMBL659748)
Ki
29±n/a nM
Citation
 Wrobleski, ST; Chen, P; Hynes, J; Lin, S; Norris, DJ; Pandit, CR; Spergel, S; Wu, H; Tokarski, JS; Chen, X; Gillooly, KM; Kiener, PA; McIntyre, KW; Patil-Koota, V; Shuster, DJ; Turk, LA; Yang, G; Leftheris, K Rational design and synthesis of an orally active indolopyridone as a novel conformationally constrained cannabinoid ligand possessing antiinflammatory properties. J Med Chem 46:2110-6 (2003) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50128095
Synonyms:
7-Methoxy-2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indole-3-carboxylic acid (1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amide | CHEMBL431363
Type:
Small organic molecule
Emp. Form.:
C27H39N3O3
Mol. Mass.:
453.6169
SMILES:
COc1cccc2c(C(=O)NC3[C@@]4(C)CC[C@H](C4)C3(C)C)c(C)n(CCN3CCOCC3)c12
Structure:
Search PDB for entries with ligand similarity: