Reaction Details Report a problem with these data
Target
Chymotrypsinogen A
Ligand
BDBM50002861
Substrate
n/a
Meas. Tech.
ChEMBL_49921 (CHEMBL664290)
IC50
200000±n/a nM
Citation
 Seidler, J; McGovern, SL; Doman, TN; Shoichet, BK Identification and prediction of promiscuous aggregating inhibitors among known drugs. J Med Chem 46:4477-86 (2003) [PubMed]  Article 
Target
Name:
Chymotrypsinogen A
Synonyms:
Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:
Serine protease
Mol. Mass.:
25670.88
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN
  
Inhibitor
Name:
BDBM50002861
Synonyms:
3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEMBL1071 | Daypro | OXAPROZIN | WY-21743 | oxaprosin
Type:
Small organic molecule
Emp. Form.:
C18H15NO3
Mol. Mass.:
293.3166
SMILES:
OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1
Structure:
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