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Target
Histone deacetylase 1
Ligand
BDBM50114834
Substrate
n/a
Meas. Tech.
ChEMBL_87858 (CHEMBL701996)
IC50
65±n/a nM
Citation
 Miller, TA; Witter, DJ; Belvedere, S Histone deacetylase inhibitors. J Med Chem 46:5097-116 (2003) [PubMed]  Article 
Target
Name:
Histone deacetylase 1
Synonyms:
Cereblon/Histone deacetylase 1 | HD1 | HDAC1 | HDAC1_HUMAN | Histone deacetylase 1 (HDAC1) | Human HDAC1 | RPD3L1
Type:
Enzyme
Mol. Mass.:
55090.27
Organism:
Homo sapiens (Human)
Description:
Q13547
Residue:
482
Sequence:
MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA
  
Inhibitor
Name:
BDBM50114834
Synonyms:
8-Oxo-8-phenyl-octanoic acid hydroxyamide | CHEMBL95959 | N-hydroxy-8-oxo-8-phenyloctanamide
Type:
Small organic molecule
Emp. Form.:
C14H19NO3
Mol. Mass.:
249.3056
SMILES:
ONC(=O)CCCCCCC(=O)c1ccccc1
Structure:
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