Reaction Details Report a problem with these data
Target
Histone deacetylase 2b
Ligand
BDBM50082659
Substrate
n/a
Meas. Tech.
ChEMBL_87877 (CHEMBL697299)
IC50
180±n/a nM
Citation
 Miller, TA; Witter, DJ; Belvedere, S Histone deacetylase inhibitors. J Med Chem 46:5097-116 (2003) [PubMed]  Article 
Target
Name:
Histone deacetylase 2b
Synonyms:
Histone deacetylase HD2
Type:
PROTEIN
Mol. Mass.:
30785.07
Organism:
Zea mays
Description:
ChEMBL_87549
Residue:
286
Sequence:
MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVEKHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQNNEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEMSEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSEQSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
  
Inhibitor
Name:
BDBM50082659
Synonyms:
4-(dimethylamino)-N-{4-[(hydroxyamino)carbonyl]benzyl}benzamide | CHEMBL142988
Type:
Small organic molecule
Emp. Form.:
C17H19N3O3
Mol. Mass.:
313.3511
SMILES:
CN(C)c1ccc(cc1)C(=O)NCc1ccc(cc1)C(=O)NO
Structure:
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