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Target
Glycogen phosphorylase, brain form
Ligand
BDBM50422216
Substrate
n/a
Meas. Tech.
ChEMBL_70998 (CHEMBL680574)
Ki
45000±n/a nM
Citation
 Pan, D; Liu, J; Senese, C; Hopfinger, AJ; Tseng, Y Characterization of a ligand-receptor binding event using receptor-dependent four-dimensional quantitative structure-activity relationship analysis. J Med Chem 47:3075-88 (2004) [PubMed]  Article 
Target
Name:
Glycogen phosphorylase, brain form
Synonyms:
Brain glycogen phosphorylase | Glycogen phosphorylase, brain form | PYGB | PYGB_HUMAN
Type:
PROTEIN
Mol. Mass.:
96699.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_70998
Residue:
843
Sequence:
MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNIPRD
  
Inhibitor
Name:
BDBM50422216
Synonyms:
CHEMBL336310
Type:
Small organic molecule
Emp. Form.:
C8H14ClNO6
Mol. Mass.:
255.653
SMILES:
OC[C@H]1O[C@@H](NC(=O)CCl)[C@H](O)[C@@H](O)[C@@H]1O
Structure:
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