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TargetGamma-carbonic anhydrase
LigandBDBM10867
Substrate/Competitorn/a
Meas. Tech.ChEMBL_303239
Ki 610±n/a nM
Citation Zimmerman, SInnocenti, ACasini, AFerry, JGScozzafava, ASupuran, CT Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides. Bioorg Med Chem Lett14:6001-6 (2004) [PubMed]  Article
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Gamma-carbonic anhydrase
Name:Gamma-carbonic anhydrase
Synonyms:CAM | Carbonic anhydrase
Type:Protein
Mol. Mass.:26390.56
Organism:Methanosarcina thermophila
Description:P40881
Residue:247
Sequence:
MMFNKQIFTILILSLSLALAGSGCISEGAEDNVAQEITVDEFSNIRENPVTPWNPEPSAP
VIDPTAYIDPQASVIGEVTIGANVMVSPMASIRSDEGMPIFVGDRSNVQDGVVLHALETI
NEEGEPIEDNIVEVDGKEYAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGN
NCVLEPRSAAIGVTIPDGRYIPAGMVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNVHLA
EGYKETS
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BDBM10867
NameBDBM10867
Synonyms:4-amino-6-chlorobenzene-1,3-disulfonamide | CHEMBL266240 | aromatic/heteroaromatic sulfonamide 12
TypeSmall organic molecule
Emp. Form.C6H8ClN3O4S2
Mol. Mass.285.728
SMILESNc1cc(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O
Structure
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