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Target
Somatostatin receptor type 2
Ligand
BDBM50169465
Substrate
n/a
Meas. Tech.
ChEMBL_310308 (CHEMBL833264)
EC50
4±n/a nM
Citation
 Contour-Galcéra, MO; Sidhu, A; Plas, P; Roubert, P 3-Thio-1,2,4-triazoles, novel somatostatin sst2/sst5 agonists. Bioorg Med Chem Lett 15:3555-9 (2005) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50169465
Synonyms:
3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl]-1-(7-methyl-1H-indol-3-yl)-propan-1-one | CHEMBL434159
Type:
Small organic molecule
Emp. Form.:
C27H28N6OS
Mol. Mass.:
484.616
SMILES:
Cc1cccc2c(c[nH]c12)C(=O)CCSc1nnc(-c2ccc3ccccc3n2)n1CCCCN
Structure:
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