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Target
Luciferin 4-monooxygenase
Ligand
BDBM50370458
Substrate
n/a
Meas. Tech.
ChEMBL_302874 (CHEMBL828788)
Ki
340±n/a nM
Citation
 Branchini, BR; Murtiashaw, MH; Carmody, JN; Mygatt, EE; Southworth, TL Synthesis of an N-acyl sulfamate analog of luciferyl-AMP: a stable and potent inhibitor of firefly luciferase. Bioorg Med Chem Lett 15:3860-4 (2005) [PubMed]  Article 
Target
Name:
Luciferin 4-monooxygenase
Synonyms:
LUCI_AQULA | Luciferase
Type:
PROTEIN
Mol. Mass.:
60126.66
Organism:
Luciola lateralis
Description:
ChEMBL_786225
Residue:
548
Sequence:
MENMENDENIVYGPEPFYPIEEGSAGAQLRKYMDRYAKLGAIAFTNALTGVDYTYAEYLEKSCCLGEALKNYGLVVDGRIALCSENCEEFFIPVLAGLFIGVGVAPTNEIYTLRELVHSLGISKPTIVFSSKKGLDKVITVQKTVTAIKTIVILDSKVDYRGYQSMDNFIKKNTPQGFKGSSFKTVEVNRKEQVALIMNSSGSTGLPKGVQLTHENAVTRFSHARDPIYGNQVSPGTAILTVVPFHHGFGMFTTLGYLTCGFRIVMLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRSELLDKYDLSNLVEIASGGAPLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWLHTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPIAGELPGAVVVLEKGKSMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGKAIREILKKPVAKM
  
Inhibitor
Name:
BDBM50370458
Synonyms:
CHEMBL610240
Type:
Small organic molecule
Emp. Form.:
C21H18N8O8S3
Mol. Mass.:
606.611
SMILES:
Nc1ncnc2n(cnc12)C1O[C@H](COS(=O)(=O)NC(=O)c2csc(n2)-c2nc3ccc(O)cc3s2)[C@@H](O)[C@H]1O |r|
Structure:
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