| Reaction Details |
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 | Report a problem with these data |
| Target | Eukaryotic translation initiation factor 4E (eIF4E) |
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| Ligand | BDBM50370489 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305877 |
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| IC50 | >400000±n/a nM |
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| Citation |  Ghosh, P; Park, C; Peterson, MS; Bitterman, PB; Polunovsky, VA; Wagner, CR Synthesis and evaluation of potential inhibitors of eIF4E cap binding to 7-methyl GTP. Bioorg Med Chem Lett15:2177-80 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Eukaryotic translation initiation factor 4E (eIF4E) |
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| Name: | Eukaryotic translation initiation factor 4E/Eukaryotic translation initiation factor 4E-binding protein 1 |
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| Synonyms: | Eukaryotic translation initation factor |
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| Type: | Protein |
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| Mol. Mass.: | 25095.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06730 |
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| Residue: | 217 |
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| Sequence: | MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
QRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIG
RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
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| BDBM50370489 |
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| Name | BDBM50370489 |
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| Synonyms: | CHEMBL607902 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17N5O4S |
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| Mol. Mass. | 315.349 |
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| SMILES | CN1CN(C2O[C@H](CO)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=S)c12 |r| |
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| Structure |  |
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| n/a |
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