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Target
Carbonic anhydrase
Ligand
BDBM10859
Substrate
n/a
Meas. Tech.
ChEMBL_347177 (CHEMBL862664)
Ki
473±n/a nM
Citation
 Nishimori, I; Vullo, D; Minakuchi, T; Morimoto, K; Onishi, S; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. Bioorg Med Chem Lett 16:2182-8 (2006) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
Beta-carbonic anhydrase | CYNT_HELPY | Carbonic anhydrase 1 | cynT | hpβCA
Type:
Protein
Mol. Mass.:
25517.77
Organism:
Helicobacter pylori (strain G27)
Description:
O24855
Residue:
221
Sequence:
MKAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVICNMGNVNPPKTSYKESLSTIASIEYAIAHVGVQNLIICGHSDCGACGSVHLIHDETTKAKTPYIANWIQFLEPVKEELKNHPQFSNHFAKRSWLTERLNARLQLNNLLSYDFIQEKASKNELKIFGWHYIIETGRIYNYNFESHFFEPIGETIKQRKSHENF
  
Inhibitor
Name:
BDBM10859
Synonyms:
4-methylbenzene-1-sulfonamide | CHEMBL574 | aromatic/heteroaromatic sulfonamide 4 | hCA inhibitor, 7
Type:
Small organic molecule
Emp. Form.:
C7H9NO2S
Mol. Mass.:
171.217
SMILES:
Cc1ccc(cc1)S(N)(=O)=O
Structure:
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