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Target
Melanocortin receptor 4
Ligand
BDBM50186366
Substrate
n/a
Meas. Tech.
ChEMBL_365697 (CHEMBL868539)
Ki
4420±n/a nM
Citation
 Odagami, T; Tsuda, Y; Kogami, Y; Kouji, H; Okada, Y Design of cyclic peptides with agonist activity at melanocortin receptor-4. Bioorg Med Chem Lett 16:3723-6 (2006) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM50186366
Synonyms:
CHEMBL211131 | c(his-L-phe-arg-trp-Aoc)
Type:
Small organic molecule
Emp. Form.:
C40H53N11O5
Mol. Mass.:
767.9195
SMILES:
NC(=N)NCCC[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)CCCCCCCNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O
Structure:
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