Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50190365
Substrate
n/a
Meas. Tech.
ChEMBL_376242 (CHEMBL869296)
Ki
>10000±n/a nM
Citation
 Zhang, Q; Keenan, SM; Peng, Y; Nair, AC; Yu, SJ; Howells, RD; Welsh, WJ Discovery of novel triazole-based opioid receptor antagonists. J Med Chem 49:4044-7 (2006) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50190365
Synonyms:
1-{3-[4-(tert-butyl) phenyl]-(1,2,4-triazol-4-yl) }-3-phenol | CHEMBL211284
Type:
Small organic molecule
Emp. Form.:
C18H19N3O
Mol. Mass.:
293.363
SMILES:
CC(C)(C)c1ccc(cc1)-c1nncn1-c1cccc(O)c1
Structure:
Search PDB for entries with ligand similarity: