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Target
Peptide deformylase, mitochondrial
Ligand
BDBM50201870
Substrate
n/a
Meas. Tech.
ChEMBL_423227 (CHEMBL912248)
IC50
360000±n/a nM
Citation
 Boularot, A; Giglione, C; Petit, S; Duroc, Y; Alves de Sousa, R; Larue, V; Cresteil, T; Dardel, F; Artaud, I; Meinnel, T Discovery and refinement of a new structural class of potent peptide deformylase inhibitors. J Med Chem 50:10-20 (2007) [PubMed]  Article 
Target
Name:
Peptide deformylase, mitochondrial
Synonyms:
DEFM_HUMAN | PDF | PDF1A | Peptide deformylase mitochondrial | Peptide deformylase, mitochondrial | Polypeptide deformylase
Type:
PROTEIN
Mol. Mass.:
27023.25
Organism:
Homo sapiens (Human)
Description:
ChEMBL_154318
Residue:
243
Sequence:
MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPPEPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPRQVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLACVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMKVND
  
Inhibitor
Name:
BDBM50201870
Synonyms:
2-(5-bromo-1H-indol-3-yl)-N-hydroxyacetamide | CHEMBL216480
Type:
Small organic molecule
Emp. Form.:
C11H11BrN2O2
Mol. Mass.:
283.121
SMILES:
ONCC(=O)Cc1c[nH]c2ccc(Br)cc12
Structure:
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