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TargetQuinone reductase 1)
LigandBDBM50195856
Substrate/Competitorn/a
Meas. Tech.ChEMBL_425055
IC50 60000±n/a nM
Citation Nolan, KATimson, DJStratford, IJBryce, RA In silico identification and biochemical characterization of novel inhibitors of NQO1. Bioorg Med Chem Lett16:6246-54 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Quinone reductase 1)
Name:Quinone reductase 1)
Synonyms:Azoreductase | DT-diaphorase | Menadione reductase | NAD(P)H dehydrogenase [quinone] 1 | NAD(P)H:quinone oxidoreductase 1 | Phylloquinone reductase | QR1 | Quinone Reductase 1 | Quinone reductase 1)
Type:Homodimer
Mol. Mass.:30874.82
Organism:Homo sapiens (Human)
Description:n/a
Residue:274
Sequence:
MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
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  Blast E-value cutoff:
BDBM50195856
NameBDBM50195856
Synonyms:CHEMBL221001 | NSC-618201
TypeSmall organic molecule
Emp. Form.C14H8O3
Mol. Mass.224.2115
SMILESOc1c2C(=O)C=CC(=O)c2cc2ccccc12 |c:5|
Structure
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n/a