Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50208813
Substrate
n/a
Meas. Tech.
ChEMBL_429489 (CHEMBL918611)
Ki
1340±n/a nM
Citation
 Adachi, H; Palaniappan, KK; Ivanov, AA; Bergman, N; Gao, ZG; Jacobson, KA Structure-activity relationships of 2,N(6),5'-substituted adenosine derivatives with potent activity at the A2B adenosine receptor. J Med Chem 50:1810-27 (2007) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50208813
Synonyms:
2-(3''-(1''-(p-toluenesulfonyl)indolyl)ethyloxy)adenosine | CHEMBL375080
Type:
Small organic molecule
Emp. Form.:
C27H28N6O7S
Mol. Mass.:
580.612
SMILES:
Cc1ccc(cc1)S(=O)(=O)n1cc(CCOc2nc(N)c3ncn([C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)c3n2)c2ccccc12
Structure:
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