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Target
Beta-lactamase
Ligand
BDBM50053173
Substrate
n/a
Meas. Tech.
ChEMBL_433470 (CHEMBL918869)
IC50
40±n/a nM
Citation
 Naas, T; Aubert, D; Ozcan, A; Nordmann, P Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii. Antimicrob Agents Chemother 51:1365-72 (2007) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
Gil1
Type:
PROTEIN
Mol. Mass.:
31369.25
Organism:
Citrobacter gillenii
Description:
ChEMBL_433470
Residue:
286
Sequence:
MPHFRLALIPLLTAFCLPAFAHPTTLNKVKEAESQLTARVGYAELDLTSGEILESYRLQERFPMMSTFKVLLCGAVLARVDAGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGPQGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQQLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYITESQATMAERNRQIAGIGATLIQHWDE
  
Inhibitor
Name:
BDBM50053173
Synonyms:
(2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda 6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide | 3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL404 | CL-298741 | TAZOBACTAM | US9120808, Tazobactam sodium salt | US9676777, TAZ | YTR-830H | Zosyn
Type:
Small organic molecule
Emp. Form.:
C10H12N4O5S
Mol. Mass.:
300.291
SMILES:
C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O |r|
Structure:
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