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Target
Beta-galactosidase
Ligand
BDBM50214383
Substrate
n/a
Meas. Tech.
ChEMBL_437033 (CHEMBL906427)
IC50
660000±n/a nM
Citation
 Kato, A; Kato, N; Adachi, I; Hollinshead, J; Fleet, GW; Kuriyama, C; Ikeda, K; Asano, N; Nash, RJ Isolation of glycosidase-inhibiting hyacinthacines and related alkaloids from Scilla socialis. J Nat Prod 70:993-7 (2007) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
Beta-gal
Type:
PROTEIN
Mol. Mass.:
79152.70
Organism:
Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903)
Description:
ChEMBL_437033
Residue:
676
Sequence:
MAKIKLKKFLYGGDYNPDQWSEDVWEQDIEFMKYYNVNAVSMPIFSWAQLQPSEDKFTFEWLDRIIDKLYSNGIHVILATPTASQPAWLSKKYPDVLPVDIHGRKRKHGARQNYCPNSPNFKNAARRIVEQMAKRYKDHPAIIMWHISNEYGPYCYCENCAKAFREWLKERYKTLDELNKRWNTAFWGHTFYDWDEIEVPSYLNEEYEYMPGRQKSSFQGLSLDYKRFMSDSLLNLYKMEVEIIKKYMPDVPVTTNLMGPFKPLDYHKWAQYMDVVSWDNYPSIKDSPHSIAFKHDLMRGLKRDQSFILMEQTPSQTNWQWYNSAKRPGMIRLLSYHAIAHGADSVLYFQWRQSVGSCEKFHSAMVPHAGHLNTRVSKELKQIGDELLRLDEILESVNKSDVALLFDWENWWALEESMGFRNDISYLEHIDSYYKALYKLKTNVDVVDPTEDLSRYKLVVAPLLYLLDSNTAKNIEEYVKNGGIFITTFLSGLVDENDRVILGGYPGWFRKLLGIWIEEIDALFPDMKNAIILEKPLGTLDGRYECDFICDVIHSEGAKVLAYYEQDYYKGMPAILENTYGSGKSVYIGTRPEQKVIEGLIKYYADMAGVKPILPVPEGVEVTKRTKDGKEYIFLLNFNNYDVCIELPQEFYELITQKLFGGRVVLRAKEVMILRK
  
Inhibitor
Name:
BDBM50214383
Synonyms:
CHEMBL388095 | [(1S*,2R*,3R*,5R*,6R*,7R*,7a*R)-3-hydroxymethyl-5-methyl-1,2,6,7-tetrahydroxypyrrolizidine]
Type:
Small organic molecule
Emp. Form.:
C9H17NO5
Mol. Mass.:
219.235
SMILES:
C[C@@H]1[C@@H](O)[C@H](O)[C@@H]2[C@H](O)[C@H](O)[C@@H](CO)N12
Structure:
Search PDB for entries with ligand similarity: