Reaction Details Report a problem with these data
Target
Iron-starvation protein PigA
Ligand
BDBM50371139
Substrate
n/a
Meas. Tech.
ChEMBL_444781 (CHEMBL895029)
Kd
15900±n/a nM
Citation
 Furci, LM; Lopes, P; Eakanunkul, S; Zhong, S; MacKerell, AD; Wilks, A Inhibition of the bacterial heme oxygenases from Pseudomonas aeruginosa and Neisseria meningitidis: novel antimicrobial targets. J Med Chem 50:3804-13 (2007) [PubMed]  Article 
Target
Name:
Iron-starvation protein PigA
Synonyms:
Heme oxygenase | Iron-starvation protein PigA
Type:
PROTEIN
Mol. Mass.:
21946.19
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_444781
Residue:
198
Sequence:
MDTLAPESTRQNLRSQRLNLLTNEPHQRLESLVKSKEPFASRDNFARFVAAQYLFQHDLEPLYRNEALARLFPGLASRARDDAARADLADLGHPVPEGDQSVREADLSLAEALGWLFVSEGSKLGAAFLFKKAAALELDENFGARHLAEPEGGRAQGWKSFVAILDGIELNEEEERLAAKGASDAFNRFGDLLERTFA
  
Inhibitor
Name:
BDBM50371139
Synonyms:
CHEMBL395101
Type:
Small organic molecule
Emp. Form.:
C13H13N7
Mol. Mass.:
267.2892
SMILES:
NC(NN=Cc1cccnc1)=NN=Cc1cccnc1 |w:3.2,13.14,11.12|
Structure:
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