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TargetDehydrogenase/reductase SDR family member 9
LigandBDBM50009859
Substrate/Competitorn/a
Meas. Tech.ChEMBL_447932
IC50 100000±n/a nM
Citation Harrak, YRosell, GDaidone, GPlescia, SSchillaci, DPujol, MD Synthesis and biological activity of new anti-inflammatory compounds containing the 1,4-benzodioxine and/or pyrrole system. Bioorg Med Chem15:4876-90 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dehydrogenase/reductase SDR family member 9
Name:Dehydrogenase/reductase SDR family member 9
Synonyms:3-alpha hydroxysteroid dehydrogenase | 3-alpha-HSD | Short-chain dehydrogenase/reductase retSDR8
Type:PROTEIN
Mol. Mass.:35223.09
Organism:Rattus norvegicus
Description:ChEMBL_447932
Residue:319
Sequence:
MLLWVLALLFLCAFLWNYKGQLKIADIADKYIFITGCDSGFGNLAARTFDRKGFRVIAAC
LTESGSEALKAKTSERLHTVLLDVTNPENVKETAQWVKSHVGEKGLWGLINNAGVLGVLA
PTDWLTVDDYREPIEVNLFGLINVTLNMLPLVKKARGRVINVSSIGGRLAFGGGGYTPSK
YAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTGLADPIKTTEKKLAIWKHLSPDIKQQYGE
GYIEKSLHRLKSSTSSVNLDLSLVVECMDHALTSLFPKTRYTAGKDAKTFWIPLSHMPAA
LQDFLLLKEKVELANPQAV
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  Blast E-value cutoff:
BDBM50009859
NameBDBM50009859
Synonyms:(+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid | (+-)-ibuprofen | (+-)-p-isobutylhydratropic acid | (4-isobutylphenyl)-alpha-methylacetic acid | (RS)-ibuprofen | 2-(4-isobutylphenyl)propanoic acid | 2-[4-(2-methylpropyl)phenyl]propanoic acid | 4-isobutylhydratropic acid | Advil | Brufen | CHEMBL521 | IBUPROFEN LYSINE | Ibuprofen | Ibuprofen (1) | Motrin | alpha-(4-isobutylphenyl)propionic acid | alpha-(p-isobutylphenyl)propionic acid
TypeSmall organic molecule
Emp. Form.C13H18O2
Mol. Mass.206.2808
SMILESCC(C)Cc1ccc(cc1)C(C)C(O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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