Reaction Details Report a problem with these data
Target
Transcriptional activator protein LuxR
Ligand
BDBM50373056
Substrate
n/a
Meas. Tech.
ChEMBL_466368 (CHEMBL932480)
IC50
2000±n/a nM
Citation
 Frezza, M; Soulère, L; Reverchon, S; Guiliani, N; Jerez, C; Queneau, Y; Doutheau, A Synthetic homoserine lactone-derived sulfonylureas as inhibitors of Vibrio fischeri quorum sensing regulator. Bioorg Med Chem 16:3550-6 (2008) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXR_ALIFS | luxR
Type:
PROTEIN
Mol. Mass.:
28563.86
Organism:
Vibrio fischeri
Description:
ChEMBL_831639
Residue:
250
Sequence:
MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
  
Inhibitor
Name:
BDBM50373056
Synonyms:
CHEMBL261163
Type:
Small organic molecule
Emp. Form.:
C9H18N2O4S
Mol. Mass.:
250.315
SMILES:
CCCCCNS(=O)(=O)NC1CCOC1=O
Structure:
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