| Reaction Details |
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 | Report a problem with these data |
| Target | Interleukin-2 (IL-2) |
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| Ligand | BDBM50229786 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_466590 |
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| Ki | 60±n/a nM |
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| Citation |  Wells, JA; McClendon, CL Reaching for high-hanging fruit in drug discovery at protein-protein interfaces. Nature450:1001-1009 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interleukin-2 (IL-2) |
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| Name: | Interleukin-2 |
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| Synonyms: | IL-2 | INN=Aldesleukin | Interleukin-2 | T-cell growth factor | TCGF |
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| Type: | Enzyme |
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| Mol. Mass.: | 17630.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P60568 |
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| Residue: | 153 |
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| Sequence: | MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRML
TFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSE
TTFMCEYADETATIVEFLNRWITFCQSIISTLT
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| BDBM50229786 |
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| Name | BDBM50229786 |
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| Synonyms: | 5-[2,3-DICHLORO-4-(5-{1-[2-(2-GUANIDINO-4-METHYL-PENTANOYLAMINO)-ACETYL]-PIPERIDIN-4-YL}-1-METHYL-1H-PYRAZOL-3-YL)-PHENOXYMETHYL]-FURAN-2-CARBOXYLIC ACID | 5-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-methyl-1-oxo-pentylamino)-acetyl]-piperidin-4-yl}-1-methyl-1H-pyrazol-3-yl)-phenoxymethyl]-furan-2-carboxylic acid | 5-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-methyl-pentanoylamino)-acetyl]-piperidin-4-yl}-1-methyl-1H-pyrazol-3-yl)-phenoxymethyl]-furan-2-carboxylic acid | CHEMBL429852 | SP-4206 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H37Cl2N7O6 |
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| Mol. Mass. | 662.564 |
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| SMILES | [#6]-[#6](-[#6])-[#6]-[#6](\[#7+]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1cc(nn1-[#6])-c1ccc(-[#8]-[#6]-c2ccc(o2)-[#6](-[#8-])=O)c(Cl)c1Cl |
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| Structure | 
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| n/a |
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