Reaction Details Report a problem with these data
Target
Nociceptin receptor
Ligand
BDBM50373360
Substrate
n/a
Meas. Tech.
ChEMBL_467785 (CHEMBL931349)
IC50
1.8±n/a nM
Citation
Okamoto, O; Kobayashi, K; Kawamoto, H; Ito, S; Satoh, A; Kato, T; Yamamoto, I; Mizutani, S; Hashimoto, M; Shimizu, A; Sakoh, H; Nagatomi, Y; Iwasawa, Y; Takahashi, H; Ishii, Y; Ozaki, S; Ohta, H Identification of novel benzimidazole series of potent and selective ORL1 antagonists. Bioorg Med Chem Lett 18:3278-81 (2008) [PubMed] Article
More Info.:
Target
Name:
Nociceptin receptor
Synonyms:
KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40702.87
Organism:
Homo sapiens (Human)
Description:
P41146
Residue:
370
Sequence:
MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALACKTSETVPRPA