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Target
Mu-type opioid receptor
Ligand
BDBM50373765
Substrate
n/a
Meas. Tech.
ChEMBL_468446 (CHEMBL929789)
EC50
9790±n/a nM
Citation
 Metcalf, MD; Aceto, MD; Harris, LS; Woods, JH; Traynor, JR; Coop, A; May, EL The influence of esters and carboxylic acids as the N-substituent of opioids. Part 1: Benzomorphans. Bioorg Med Chem 16:869-73 (2008) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44431.62
Organism:
MOUSE
Description:
OPIATE Mu OPRM1 MOUSE::P42866
Residue:
398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50373765
Synonyms:
CHEMBL271026
Type:
Small organic molecule
Emp. Form.:
C16H21NO3
Mol. Mass.:
275.3428
SMILES:
C[C@H]1C2Cc3ccc(O)cc3[C@@]1(C)CCN2CC(O)=O |w:2.2,TLB:9:10:1:13.15.14,16:15:1:4.10.3|
Structure:
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