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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50373842
Substrate/Competitorn/a
Meas. Tech.ChEMBL_468586
Ki 13.6±n/a nM
Citation Colabufo, NAAbate, CContino, MInglese, CFerorelli, SBerardi, FPerrone, R Tritium radiolabelling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization. Bioorg Med Chem Lett18:2183-7 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma opioid receptor
Synonyms:Opioid receptor | Sigma | Sigma opioid receptor | Sigma-1
Type:Enzyme Catalytic Domain
Mol. Mass.:25266.54
Organism:RAT
Description:Q9R0C9
Residue:223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50373842
NameBDBM50373842
Synonyms:CHEMBL1162973
TypeSmall organic molecule
Emp. Form.C24H38N2O
Mol. Mass.370.5713
SMILESCOc1cccc2[C@H](CCCN3CCN(CC3)C3CCCCC3)CCCc12 |r,@:11,14,@@:17|
Structure
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