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Target
Melanocortin receptor 5
Ligand
BDBM50374118
Substrate
n/a
Meas. Tech.
ChEMBL_468954 (CHEMBL951293)
EC50
>100000±n/a nM
Citation
 Joseph, CG; Wilson, KR; Wood, MS; Sorenson, NB; Phan, DV; Xiang, Z; Witek, RM; Haskell-Luevano, C The 1,4-benzodiazepine-2,5-dione small molecule template results in melanocortin receptor agonists with nanomolar potencies. J Med Chem 51:1423-31 (2008) [PubMed]  Article 
Target
Name:
Melanocortin receptor 5
Synonyms:
MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R)
Type:
Enzyme
Mol. Mass.:
36966.58
Organism:
Mus musculus (Mouse)
Description:
P41149
Residue:
325
Sequence:
MNSSSTLTVLNLTLNASEDGILGSNVKNKSLACEEMGIAVEVFLTLGLVSLLENILVIGAIVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDSMICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIYYESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRTSMKGAITLTMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQEMRRTFKEIVCCHGFRRPCRLLGGY
  
Inhibitor
Name:
BDBM50374118
Synonyms:
CHEMBL270689
Type:
Small organic molecule
Emp. Form.:
C20H22N2O2
Mol. Mass.:
322.4009
SMILES:
CCCCN1c2ccccc2C(=O)NC(Cc2ccccc2)C1=O |w:14.15|
Structure:
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