Reaction Details Report a problem with these data
Target
Proline iminopeptidase
Ligand
BDBM50374363
Substrate
n/a
Meas. Tech.
ChEMBL_469257 (CHEMBL949939)
Ki
500±n/a nM
Citation
 Maryanoff, BE; Costanzo, MJ Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality. Bioorg Med Chem 16:1562-95 (2008) [PubMed]  Article 
Target
Name:
Proline iminopeptidase
Synonyms:
PAP | PIP_SERMA | Prolyl aminopeptidase | pip
Type:
PROTEIN
Mol. Mass.:
36080.68
Organism:
Serratia marcescens
Description:
ChEMBL_469257
Residue:
317
Sequence:
MEQLRGLYPPLAAYDSGWLDTGDGHRIYWELSGNPNGKPAVFIHGGPGGGISPHHRQLFDPERYKVLLFDQRGCGRSRPHASLDNNTTWHLVADIERLREMAGVEQWLVFGGSWGSTLALAYAQTHPERVSEMVLRGIFTLRKQRLHWYYQDGASRFFPEKWERVLSILSDDERKDVIAAYRQRLTSADPQVQLEAAKLWSVWEGETVTLLPSRESASFGEDDFALAFARIENHYFTHLGFLESDDQLLRNVPLIRHIPAVIVHGRYDMACQVQNAWDLAKAWPEAELHIVEGAGHSYDEPGILHQLMIATDRFAGK
  
Inhibitor
Name:
BDBM50374363
Synonyms:
CHEMBL403772
Type:
Small organic molecule
Emp. Form.:
C11H17N3O2
Mol. Mass.:
223.2716
SMILES:
CC(C)(C)c1nnc(o1)C(=O)[C@@H]1CCCN1 |r|
Structure:
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