Reaction Details Report a problem with these data
Target
Fibroblast growth factor 1
Ligand
BDBM50374508
Substrate
n/a
Meas. Tech.
ChEMBL_469445 (CHEMBL946803)
Kd
21800±n/a nM
Citation
 Liu, L; Bytheway, I; Karoli, T; Fairweather, JK; Cochran, S; Li, C; Ferro, V Design, synthesis, FGF-1 binding, and molecular modeling studies of conformationally flexible heparin mimetic disaccharides. Bioorg Med Chem Lett 18:344-9 (2008) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 1
Synonyms:
Acidic fibroblast growth factor | Beta-endothelial cell growth factor | ECGF-beta | FGF1 | FGF1_HUMAN | FGFA | Fibroblast growth factor 1 (FGF-1) | HBGF-1 | Heparin-binding growth factor 1 | aFGF
Type:
Protein
Mol. Mass.:
17461.01
Organism:
Homo sapiens (Human)
Description:
P05230
Residue:
155
Sequence:
MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
  
Inhibitor
Name:
BDBM50374508
Synonyms:
CHEMBL1627092
Type:
Small organic molecule
Emp. Form.:
C13H19O26S5
Mol. Mass.:
751.602
SMILES:
CO[C@@H]1O[C@H](COS([O-])(=O)=O)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@H](O)[C@H](O)[C@H]2OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O
Structure:
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