Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50375100
Substrate
n/a
Meas. Tech.
ChEMBL_470256 (CHEMBL950211)
IC50
840±n/a nM
Citation
 Kang, SY; Lee, SH; Seo, HJ; Jung, ME; Ahn, K; Kim, J; Lee, J Tetrazole-biarylpyrazole derivatives as cannabinoid CB1 receptor antagonists. Bioorg Med Chem Lett 18:2385-9 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50375100
Synonyms:
CHEMBL270663
Type:
Small organic molecule
Emp. Form.:
C23H21Cl3N6
Mol. Mass.:
487.812
SMILES:
CCc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1nnnn1C1CCCC1
Structure:
Search PDB for entries with ligand similarity: