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Target
Casein kinase II subunit alpha
Ligand
BDBM50229971
Substrate
n/a
Meas. Tech.
ChEMBL_473871 (CHEMBL939204)
IC50
200±n/a nM
Citation
 Fedorov, O; Marsden, B; Pogacic, V; Rellos, P; Müller, S; Bullock, AN; Schwaller, J; Sundström, M; Knapp, S A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proc Natl Acad Sci U S A 104:20523-8 (2007) [PubMed]  Article 
Target
Name:
Casein kinase II subunit alpha
Synonyms:
CK II subunit alpha | CSK2A_SCHPO | cka1 | orb5
Type:
PROTEIN
Mol. Mass.:
39531.86
Organism:
Schizosaccharomyces pombe 972h-
Description:
ChEMBL_473871
Residue:
332
Sequence:
MNQTEAAPVVSVSRVYAHVNEEMPREYWDYENMQEVFGYQDNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVKYKKIKREIKILQNLAGGPNIISLLDIVRDPESKTPSLIFEFVDNIDFRTLYPTLSDYDIRYYSYELLKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGMEYNVRVASRYFKGPELLVDFREYDYSLDIWSFGVMFAALIFKKDTFFRGRDNYDQLVKIAKVLGTDELFAYVQKYQIVLDRQYDNILGQYPKRDWYSFVNRDNRSLANDEAIDLLNRLLRYDHQERLTCQEAMAHPYFQVLK
  
Inhibitor
Name:
BDBM50229971
Synonyms:
4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl)benzamide | 4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide | 4-[4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide | CHEMBL410456
Type:
Small organic molecule
Emp. Form.:
C23H18N4O3
Mol. Mass.:
398.414
SMILES:
NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc2OCCOc2c1)-c1ccccn1
Structure:
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