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Target5-Hydroxytryptamine receptor 7 (5-HT7)
LigandBDBM50375929
Substrate/Competitorn/a
Meas. Tech.ChEMBL_474639
IC50 48±n/a nM
Citation Na, YHHong, SHLee, JHPark, WKBaek, DJKoh, HYCho, YSChoo, HPae, AN Novel quinazolinone derivatives as 5-HT7 receptor ligands. Bioorg Med Chem16:2570-8 (2008) [PubMed]  Article
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5-Hydroxytryptamine receptor 7 (5-HT7)
Name:Serotonin (5-HT) receptor
Synonyms:5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5-hydroxytryptamine receptor 7 | 5HT7 | HTR7
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:53573.08
Organism:Homo sapiens (Human)
Description:P34969
Residue:479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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BDBM50375929
NameBDBM50375929
Synonyms:CHEMBL259001
TypeSmall organic molecule
Emp. Form.C32H36FN5O4
Mol. Mass.573.6577
SMILESCCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2OC)CC1 |(14.3,-22.53,;15,-22.09,;15.73,-22.49,;16.43,-22.06,;17.15,-22.45,;17.86,-22.02,;17.83,-21.19,;17.11,-20.8,;16.41,-21.23,;15.68,-20.84,;14.98,-21.27,;14.26,-20.88,;14.23,-20.06,;13.52,-19.65,;12.8,-20.06,;12.09,-19.65,;11.38,-20.06,;11.38,-20.89,;10.66,-19.65,;9.95,-20.07,;9.23,-19.66,;8.51,-20.07,;7.79,-19.66,;7.07,-20.07,;6.36,-19.66,;6.36,-18.83,;5.65,-18.42,;7.07,-18.42,;7.79,-18.83,;8.5,-18.41,;8.5,-17.58,;9.23,-18.82,;9.94,-18.41,;10.66,-18.82,;11.37,-18.41,;11.37,-17.58,;10.65,-17.17,;9.94,-17.59,;9.22,-17.18,;9.21,-16.35,;14.93,-19.62,;15.66,-20.02,)|
Structure
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