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Target5-Hydroxytryptamine receptor 7 (5-HT7)
LigandBDBM50375933
Substrate/Competitorn/a
Meas. Tech.ChEMBL_474639
IC50 210±n/a nM
Citation Na, YHHong, SHLee, JHPark, WKBaek, DJKoh, HYCho, YSChoo, HPae, AN Novel quinazolinone derivatives as 5-HT7 receptor ligands. Bioorg Med Chem16:2570-8 (2008) [PubMed]  Article
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5-Hydroxytryptamine receptor 7 (5-HT7)
Name:Serotonin (5-HT) receptor
Synonyms:5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5-hydroxytryptamine receptor 7 | 5HT7 | HTR7
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:53573.08
Organism:Homo sapiens (Human)
Description:P34969
Residue:479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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BDBM50375933
NameBDBM50375933
Synonyms:CHEMBL260902
TypeSmall organic molecule
Emp. Form.C31H35N5O4
Mol. Mass.541.6407
SMILESCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccccc3c(=O)n2-c2ccccc2OC)CC1 |(14.36,-8.25,;15.08,-8.64,;15.79,-8.21,;16.51,-8.6,;17.22,-8.17,;17.19,-7.34,;16.47,-6.95,;15.77,-7.38,;15.04,-7,;14.34,-7.43,;13.61,-7.04,;13.59,-6.21,;12.88,-5.8,;12.16,-6.21,;11.45,-5.8,;10.73,-6.22,;10.74,-7.04,;10.02,-5.81,;9.31,-6.22,;8.59,-5.81,;7.87,-6.23,;7.15,-5.82,;6.43,-6.23,;5.72,-5.81,;5.72,-4.99,;6.43,-4.57,;7.15,-4.98,;7.86,-4.56,;7.86,-3.74,;8.59,-4.98,;9.3,-4.56,;10.01,-4.98,;10.73,-4.56,;10.72,-3.74,;10,-3.33,;9.29,-3.74,;8.58,-3.33,;8.57,-2.51,;14.29,-5.78,;15.02,-6.17,)|
Structure
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