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Target
D(2) dopamine receptor
Ligand
BDBM50354525
Substrate
n/a
Meas. Tech.
ChEMBL_476020 (CHEMBL927100)
Ki
330±n/a nM
Citation
 Volk, B; Barkóczy, J; Hegedus, E; Udvari, S; Gacsályi, I; Mezei, T; Pallagi, K; Kompagne, H; Lévay, G; Egyed, A; Hársing, LG; Spedding, M; Simig, G (Phenylpiperazinyl-butyl)oxindoles as selective 5-HT7 receptor antagonists. J Med Chem 51:2522-32 (2008) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50354525
Synonyms:
CHEMBL411663
Type:
Small organic molecule
Emp. Form.:
C22H26FN3O
Mol. Mass.:
367.4597
SMILES:
Fc1ccc2NC(=O)C(CCCCN3CCN(CC3)c3ccccc3)c2c1 |w:8.8|
Structure:
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